Rubén Francés Selected Research

Bacterial Antigens

8/2023	Bacterial translocation occurs early in cirrhosis and triggers a selective inflammatory response.
6/2022	Paneth Cells Regulate Lymphangiogenesis under Control of Microbial Signals during Experimental Portal Hypertension.
1/2021	Bacterial Translocation as Inflammatory Driver in Crohn's Disease.
1/2020	Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients.
12/2018	Regulatory T Cells Restrict Permeability to Bacterial Antigen Translocation and Preserve Short-Chain Fatty Acids in Experimental Cirrhosis.
1/2017	Toll-like receptor polymorphisms compromise the inflammatory response against bacterial antigen translocation in cirrhosis.
7/2014	Protective effect of Bifidobacterium pseudocatenulatum CECT7765 against induced bacterial antigen translocation in experimental cirrhosis.

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Rubén Francés Research Topics

Disease

48	Fibrosis (Cirrhosis) 04/2024 - 07/2002
16	Inflammation (Inflammations) 08/2023 - 01/2011
15	Ascites 10/2019 - 07/2002
9	Crohn Disease (Crohn's Disease) 01/2024 - 08/2011
9	Peritonitis 01/2020 - 12/2002
7	Liver Diseases (Liver Disease) 01/2023 - 02/2013
6	Infections 08/2023 - 06/2004
5	Bacterial Infections (Bacterial Infection) 01/2018 - 12/2002
5	Necrosis 02/2014 - 06/2004
4	Melanoma (Melanoma, Malignant) 02/2022 - 01/2015
3	Non-alcoholic Fatty Liver Disease 08/2023 - 01/2020
3	Portal Hypertension 06/2022 - 08/2019
2	Pancreatitis 03/2024 - 05/2017
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2024 - 04/2009
2	Disease Progression 01/2024 - 05/2017
2	Insulin Resistance 08/2023 - 07/2014
2	Hepatocellular Carcinoma (Hepatoma) 07/2023 - 01/2018
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021 - 02/2014
2	Obesity 01/2021 - 01/2020
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 01/2018
2	Endotoxemia 10/2019 - 09/2011
2	Hepatic Encephalopathy 10/2019 - 01/2017
1	Dysbiosis 01/2023
1	Ulcerative Colitis 11/2021
1	Ileal Diseases 01/2021
1	Hidradenitis Suppurativa 03/2020
1	Polyps 01/2020
1	Colonic Polyps 01/2020
1	End Stage Liver Disease 10/2019
1	Hepatitis 01/2018
1	Alcoholic Fatty Liver 01/2018
1	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2018

Drug/Important Bio-Agent (IBA)

26	Bacterial DNAIBA 03/2020 - 07/2002
16	CytokinesIBA 01/2024 - 12/2002
11	Norfloxacin FDA Link 01/2020 - 09/2006
7	Bacterial AntigensIBA 08/2023 - 07/2014
7	Interleukin-6 (Interleukin 6)IBA 07/2023 - 06/2004
6	Carbon Tetrachloride (Tetrachloromethane)IBA 12/2018 - 12/2010
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 09/2006
5	EndotoxinsIBA 10/2014 - 07/2007
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2010 - 12/2002
4	InflammasomesIBA 02/2022 - 01/2015
4	Anti-Bacterial Agents (Antibiotics)IBA 11/2015 - 03/2008
3	AntigensIBA 01/2023 - 02/2016
3	AlbuminsIBA 01/2021 - 12/2018
3	Interleukin-10 (Interleukin 10)IBA 01/2019 - 01/2011
2	nasIBA 04/2024 - 01/2021
2	MicroRNAs (MicroRNA)IBA 01/2024 - 01/2018
2	Insulin (Novolin)FDA Link 08/2023 - 01/2020
2	beta Adrenergic ReceptorsIBA 09/2020 - 01/2012
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 01/2020
2	C-Reactive ProteinIBA 01/2020 - 01/2019
2	Butyrates (Butyrate)IBA 10/2019 - 01/2011
2	Interleukin-18 (Interleukin 18)IBA 05/2017 - 01/2015
2	Phenobarbital (Luminal)FDA Link 02/2016 - 10/2014
1	2-mercaptopurineIBA 03/2024
1	Kazal Pancreatic Trypsin InhibitorIBA 03/2024
1	C-Type Lectins (C-Type Lectin)IBA 01/2024
1	human MIRN376A1 microRNAIBA 01/2024
1	Fatty Acids (Saturated Fatty Acids)IBA 08/2023
1	Biomarkers (Surrogate Marker)IBA 08/2023
1	LipidsIBA 08/2023
1	LipopolysaccharidesIBA 08/2023
1	lipoteichoic acidIBA 08/2023
1	Bile Acids and Salts (Bile Acids)IBA 01/2023
1	ChemokinesIBA 03/2022
1	Ustekinumab (CNTO 1275)FDA Link 11/2021
1	Dietary Fiber FDA Link 01/2021
1	BilirubinIBA 01/2021
1	CarbonIBA 01/2021
1	bisphenol AIBA 01/2021
1	Adrenergic Receptors (Adrenergic Receptor)IBA 09/2020
1	Adrenergic Agents (Adrenergic Drugs)IBA 09/2020
1	CatecholaminesIBA 09/2020
1	Interleukin-23 (Interleukin 23)IBA 01/2020
1	Interleukin-2 (IL2)IBA 01/2020
1	Interleukin-17 (Interleukin 17)IBA 01/2020
1	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020
1	Interleukin-4 (Interleukin 4)IBA 01/2020
1	Butyric Acid (Butanoic Acid)IBA 10/2019
1	Simvastatin (Zocor)FDA LinkGeneric 08/2019
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	Infliximab (Remicade)FDA Link 01/2019
1	Adalimumab (Humira)FDA Link 01/2019
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 12/2018
1	NLR ProteinsIBA 12/2018
1	Volatile Fatty AcidsIBA 12/2018
1	interleukin 20 (IL-20)IBA 01/2018
1	Cytokine Receptors (Cytokine Receptor)IBA 01/2018
1	Rifaximin (L 105)FDA Link 01/2018
1	Interleukin-22 (IL-22)IBA 01/2018
1	Messenger RNA (mRNA)IBA 05/2017
1	Lactulose (Duphalac)FDA LinkGeneric 01/2017

Therapy/Procedure

5	Liver Transplantation 07/2023 - 01/2018
3	Ligation 06/2022 - 10/2014
3	Therapeutics 07/2015 - 01/2013
2	Oral Administration 06/2019 - 01/2018
1	Immunomodulation 01/2020
1	Surgical Portasystemic Shunt (Portosystemic Shunt) 10/2019